Welcome to the Michigan CTA Biomolecular NMR Facility. The NMR Facility is dedicated to providing Michigan with state-of-the-art NMR instrumentation as well as exceptional NMR expertise. The Facility has a group of instruments housed at Michigan State University (900 MHz), University of Michigan (600 MHz), and Wayne State University (700 MHz) for both solution- and solid-state biomolecular NMR applications. It is a core resource of the Michigan State University based Michigan Center for Structural Biology (MCSB). MCSB is one of the five major facilities supported by MLSC/CTA that provides a platform of modern instrumentation to examine the structure-function relationships of biomacromolecules. The instruments at each member institution are locally administrated following the policies and rates established by a statewide NMR committee and approved by MLSC/CTA. NMR time and service are scheduled via an online request form. A general description of sample requirements for NMR analysis can be found here. For more information on facility usage and services, please contact Dr. Aizhuo Liu, the Director of Biomolecular NMR Facility at Michigan State University.

Together with X-ray crystallography, NMR spectroscopy is one of the two leading technologies for the structure determination of biomacromolecules at atomic resolution. In addition, NMR provides unique and important molecular motional and interaction profiles that contain pivotal information on the functions of biomacromolecules. The information is not only important for the understanding of life processes at the molecular level but also for drug development.